Sr. Software Algorithm Engineer

Occupation: Biotech/R&D/Science Pacific Biosciences, Inc. is a startup life science instrument company focused on ultra-fast DNA sequencing. PacBio will design and manufacture instruments, chips and bio-reagents for the single molecule sequencing of DNA. Based on pioneering work done at Cornell University, the company is now venture funded by world class venture capitalists. PacBio is commercializing a DNA sequencing technology that will replace other techniques to become the "gold standard" for nucleic acid analysis and enable sequencing of individual genomes as part of routine medical care. PACIFIC BIOSCIENCES seeks the brightest and the best individuals in the fields of nanotechnology, biochemistry, optics, high speed digital design and bioinformatics. You must be creative, forward thinking, approach challenges with an innovative attitude, and enjoy being part of a highly interdisciplinary team. If this is you, we would like to hear from you! Sr. Software Algorithm Engineer The ideal candidate will have a B.S. or M.S. or Ph.D. in engineering, computer science, physics or related fields with several years experience in statistics and statistical processes to verify complex algorithms and tools that are used to identify signals in sensor data from single-molecule sequencing. He or she will be working in a fast-paced start-up, interacting with scientists and engineers from a variety of backgrounds. The candidate will be responsible to ensure the quality of the signal analysis and classification algorithms. S/He will work on the simulator to generate input signals to characterize the penalties of the analysis pipeline. The candidate will define metrics and develop test protocols and tools to ensure the performances of the algorithms. He or she will work closely with the SW engineers to define specifications and develop test plans. The candidate will understand and resolve performance issues, document results and report test data to the different teams. Excellent analytical and problem solving skills, he or she must be a strong team player, able to take initiative, and detail oriented. Position Requirements: - Advanced degree, or equivalent experience, in math, physics, engineering or related fields. - Minimum of 5 years of experience in developing and executing software and hardware test plans. - Experience with Bayesian/maximum-likelihood estimators, clustering algorithms, and Monte-Carlo style simulation - Software development skills and experience with C#/C++/C required - Experience with Matlab or Matlab like tools desired, Python, Perl desired. - Experience with hidden-Markou models and/or speech recognition - Excellent interpersonal, communication and presentation skills - Any knowledge of the following disciplines is helpful: molecular biology, biochemistry, bioinformatics, statistical mechanics, genetic algorithms - Product development and / or industry experience in a multi-disciplinary Biotech environment is a plus.