Senior Development Associate Scientist

Senior Development Associate Scientist

AlphaVax, Inc., located near Research Triangle Park, N.C., is seeking a talented Senior Development Associate Scientis.  AlphaVax is a rapidly growing biotech vaccine company that is developing a new generation of human vaccines based on a unique viral vector delivery system.  The AlphaVax vector system constitutes a major advance in vaccine technology and has the potential to exert a significant influence on the future course of the vaccine industry. A broad- based immune response, safety profile, and protection data on challenge have been established in animal models and suggest that the vector system may stimulate immunity to diseases not currently preventable with vaccines.  Immediate applications of the technology include a variety of preventative and therapeutic vaccines for infectious diseases and cancer.OVERVIEW:
As a Sr. Development Associate Scientist, you will perform cell culture process development activities as part of a project team with a focus on developing methods and processes for the production of viral vaccines.

RESPONSIBILITIES: Perform vaccine production process development activities using roller bottles and stirred tank and disposable bioreactors up to 250L scale. Optimize process conditions to improve product yield.  Advance scale up strategy for vaccine production. Assist in developing large scale virus harvest procedures.Implement new methods and technologies to enhance operations.Support the design, installation and transfer of upstream process equipment and procedures into a cGMP facility.Insure all materials are available and inventoried. Develop and review SOPs, batch records, technical documents and reports.


QUALIFICATIONS:
A combination of education and industry experience:BS/MS with a broad background in small-scale bioreactor operation (stirred tank and disposable)/optimization, and GMP process development and tech transfer, ideally with practical knowledge of viral propagation. 5+ years mammalian cell culture and process development experience. Experience with anchorage dependent cell lines is a plus.Experience with design of experiments and statistical analysis is desired. Strong written and verbal communication skills as well as the ability to work in a cross functional team environment are required.

 Please Note: Candidates who apply should describe specific related experience.

AlphaVax offers competitive compensation, an attractive benefits package, the opportunity for professional advancement, and career growth.  If you meet the position requirements and are seeking an opportunity to contribute in a challenging, small company environment, please submit a resume and salary history to email your resume to: humanresourc es@alphavax.com .  AlphaVax is an Equal Opportunity Employer.