Process Chemist (Senior Scientist)

 



Isis Pharmaceuticals, Inc. is a leading drug discovery and development company, focused exclusively on the therapeutic target, RNA. Founded in 1989, Isis' mission is to develop products from its RNA-based technologies, such as antisense. Very little was known about antisense when the Company was first established, but its founders envisioned an opportunity to revolutionize the pharmaceutical industry with a more efficient and targeted means of drug discovery. Since then, Isis scientists have made tremendous progress advancing the science of antisense, unveiling capabilities that have far exceeded their expectations.

PROCESS CHEMIST (SENIOR SCIENTIST)

DESCRIPTION:

Seeking a motivated chemist to join our Process Chemistry group at the Senior Scientist level.  The successful candidate will work closely with drug substance manufacturing personnel to design and optimize solid-phase approaches for the synthesis of therapeutic oligonucleotides.  The candidate will possess a strong work ethic, excellent communication skills and have demonstrated a record of implementing process improvements. 

 

REQUIREMENTS:

The successful candidate will possess the following:

 Ph.D. in Physical Organic Chemistry or Organic Chemistry2-5 years experience in process researchFamiliarity with standard analytical techniques such as HPLC, LCMS and NMRExperience in the statistical design of experiments (DOE)Experience in process scale-up and transferExcellent oral and written communication skillsAbility to carry through on assignments and meet deadlines and time schedulesAbility to be flexible with workload and job duties to support team objectivesAbility to work independentlyStrong interpersonal skills and ability to be successful in a team environmentPrior experience with oligonucleotides is a plus

Excellent salary and benefits package offered. 

For immediate consideration, please apply online by visiting our website, www.isispharm.com.  Reference Requisition #89. NO PHONE CALLS PLEASE.  PRINCIPALS ONLY.

Isis Pharmaceuticals, Inc. is proud to be an EEO/AA M/F D/V employer.